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The team combined various national data sources (mortality, demographic, economic, and geographic) in a multi-method analysis of missing drug classification in the overdose mortality records (as defined using ICD-10 code T50.9 on death certificates)

For the majority of instances where significant differences were no longer detected, stratum-specific sample sizes were small and substantial disparities in the point estimates were observed (see detailed data in Table S1)

Of course there are people who smoke and are healthy or who dont smoke but arent healthy

Ann Glob Health

Are pipe tobacco and cigarette tobacco chemically different